Thursday, October 18, 2018

"Organoids Could Aid Cancer Drug Selection" - news out of DF


A big shout-out to Donna who posted this article from Dana Farber Insight.

Organoids are miniature versions of the tissue or organ they were taken from and therefore replicate faithfully cellular structures.

The key points in this article were:

  • Tests on living 'organoids' created from patients' ovarian cancer cells proved more accurate than DNA sequencing in prediction tumors' sensitivity or resistance to chemotherapy drugs
  • Ovarian cancer organoids were developed from patient tumor samples in just seven to ten days, instead of weeks or months, allowing for rapid, direct tests of drugs and drug combinations.
  • The organoids created in this study were found to contain immune cells, raising the prospect of testing immunotherapy drugs for ovarian cancer, the scientists say.
To read the article in its entirety, follow this link.

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