Organoids are miniature versions of the tissue or organ they were taken from and therefore replicate faithfully cellular structures.
The key points in this article were:
- Tests on living 'organoids' created from patients' ovarian cancer cells proved more accurate than DNA sequencing in prediction tumors' sensitivity or resistance to chemotherapy drugs
- Ovarian cancer organoids were developed from patient tumor samples in just seven to ten days, instead of weeks or months, allowing for rapid, direct tests of drugs and drug combinations.
- The organoids created in this study were found to contain immune cells, raising the prospect of testing immunotherapy drugs for ovarian cancer, the scientists say.
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