Sunday, September 17, 2017
Gene Therapy Approach for Ovarian Cancer Shows Encouraging Signs in Animal Model
Here's the copy of the article:
A single injection of a gene therapy viral vector can deliver effective and long-lasting levels of a protein that inhibits the growth of some mouse tumors derived from patients with recurrent ovarian cancer, according to a new study published July 27 in the Proceedings of the National Academy of Sciences.
Mullerian inhibiting substance (MIS) is a protein produced in the male testis during early development. In the developing male fetus, precursor cells that would become the fallopian tubes, uterus, cervix, and vagina of a female, express receptors to MIS, which causes these tissues to regress.